Cyclic peptides space: The methodology of sequence selection to cover the comprehensive physical properties. bioRxiv. 2026 Mar 12;2026.03.10.710724. https://doi.org/10.64898/2026.03.10.710724
De novo design of a peptide ligand for specific affinity purification of human complement C1q. bioRxiv. 2026 Apr 1;2026.03.30.714096. https://doi.org/10.64898/2026.03.30.714096
Long-term effectiveness, safety, and cost-effectiveness of intravenous immunoglobulin for generalized myasthenia gravis in an era of molecular targeted drugs: Insights from Japanese post-marketing surveillance. J Autoimmun. 2026 Jun 11;162:103588. https://doi.org/10.1016/j.jaut.2026.103588
Disseminated intravascular coagulation resolution as a surrogate outcome for mortality in sepsis-associated disseminated intravascular coagulation. Thromb Res. 2025 Nov;255:109485. https://doi.org/10.1016/j.thromres.2025.109485
Factors influencing antithrombin activity following supplementation in sepsis-associated disseminated intravascular coagulation. Thromb J. 2025 Oct 6;23(1):90. https://doi.org/10.1186/s12959-025-00779-9
Development of Experimental Models of Antithrombin-independent Heparin Resistance Using Platelet Factor 4 and the Effect of Antithrombin in These Models. J Cardiothorac Vasc Anesth. 2025 Sep;39(9):2284-2292. https://doi.org/10.1053/j.jvca.2025.05.045
Survey and Establishment of Points to Consider for Application of Analytical Techniques to Evaluate Protein Aggregates and Insoluble Particles in Biopharmaceuticals: Experiences in Japan Biopharmaceutical Consortium. AAPS J. 2025 Apr 3;27(3):75. https://doi.org/10.1208/s12248-025-01056-3
血漿分画製剤の過去・現在・未来 薬史学雑誌 60 (1) 11-17, (2025)
2024年
Antibodies Against Glutamic Acid Decarboxylase in Intravenous Immunoglobulin Preparations Can Affect the Diagnosis of Type 1 Diabetes Mellitus. Vox Sang. 2024 Oct;119(10):1106-1110. https://doi.org/10.1111/vox.13710
Anti-monkeypox virus-neutralizing activities of human immunoglobulin manufactured between 1999 and 2021 and derived from donors in the United States and Japan. Vox Sang. 2024 Aug;119(8):878-882. https://doi.org/10.1111/vox.13655
Determining prognostic indicator for anticoagulant therapy in sepsis-induced disseminated intravascular coagulation. J Intensive Care. 2024 Jun 24;12(1):24. https://doi.org/10.1186/s40560-024-00739-x
Autoantibody Profiles in Intravenous Immunoglobulin Preparations: A Possible Cause of Mistaken Autoimmunity Diagnosis. Transfusion. 2024 Apr;64(4):597-605. https://doi.org/10.1111/trf.17766
血漿分画製剤と移植 Precision Medicine 7巻13号1069-1075, (2024)
2023年
Risk stratification utilizing sequential organ failure assessment (SOFA) score, antithrombin activity, and demographic data in sepsis-associated disseminated intravascular coagulation (DIC). Sci Rep. 2023 Dec 15;13(1):22502. https://doi.org/10.1038/s41598-023-49855-y
The antithrombin activity recovery after substitution therapy is associated with improved 28-day mortality in patients with sepsis-associated disseminated intravascular coagulation. Thromb J. 2023 Nov 2;21(1):112. https://doi.org/10.1186/s12959-023-00556-6
Changes in Anti-SARS-CoV-2 Antibody Titers of Pooled Plasma Derived From Donors in Japan: A Potential Tool for Mass-Immunity Evaluation. J Infect Dis. 2023 Oct 3;228(7):889-894. https://doi.org/10.1093/infdis/jiad178
High doses of intravenous immunoglobulin stimulate regulatory T cell and suppress natural killer cell in women with recurrent pregnancy loss. J Reprod Immunol. 2023 Aug;158:103977. https://doi.org/10.1016/j.jri.2023.103977
Decline in intravenous immunoglobulin titer against influenza virus A/H2N2 derived from donors in Japan. J Med Virol. 2023 Mar;95(3):e28685. https://doi.org/10.1002/jmv.28685
2022年
A Collaborative Study on the Classification of Silicone Oil Droplets and Protein Particles Using Flow Imaging Method. J Pharm Sci. 2022 Oct;111(10):2745-2757. https://doi.org/10.1016/j.xphs.2022.07.006
Intravenous Immunoglobulin Suppresses Chemotherapy-Induced Peripheral Neurotoxicity Via Macrophage Modulation in Rats and Mice. Eur. Soc. Med. 2022 Oct;10 (10): 2375-1924. https://doi.org/10.18103/mra.v10i10.3163
Intravenous Ig Regulates Anti-Desmoglein 3 IgG Production in B220– Antibody-Producing Cells in Mice with Pemphigus Vulgaris. J Invest Dermatol. 2022 Jul;142(7):1786-1792.e3. https://doi.org/10.1016/j.jid.2021.11.022
Long-term monitoring of antibody titers against microorganisms in human intravenous immunoglobulin lots derived from healthy donors in Japan manufactured during 1998-2018. Transfusion. 2022 Jul;62(7):1417-1426. https://doi.org/10.1111/trf.16938
Intravenous immunoglobulin treatment in women with four or more recurrent pregnancy losses: A double-blind, randomised, placebo-controlled trial. EClinicalMedicine. 2022 Jun 29;50:101527. https://doi.org/10.1016/j.eclinm.2022.101527
2021年
Phenotypic Characterization of Cell Culture-Derived Hepatitis E Virus Subjected to Different Chemical Treatments: Application in Virus Removal via Nanofiltration. J Virol Methods. 2021 Oct:296:114244. https://doi.org/10.1016/j.jviromet.2021.114244
Assessment of the potentially decreased neutralizing activities of intravenous immunoglobulin against future coronavirus variants. Transfusion. 2021 Aug;61(8):2514-2515. https://doi.org/10.1111/trf.16553
Screening for parvovirus B19 antigen through chemiluminescent enzyme immunoassay is equivalent to B19 nucleic acid amplification test-based screening of pooled plasma. Transfusion. 2021 Aug;61(8):2240-2244. https://doi.org/10.1111/trf.16512
Virus Neutralization by Human Intravenous Immunoglobulin Against Influenza Virus Subtypes A/H5 and A/H7. Biologics. 2021 Apr 13;15:87-94. https://doi.org/10.2147/BTT.S291808
Neutralizing and binding activities against SARS-CoV-1/2, MERS-CoV, and human coronaviruses 229E and OC43 by normal human intravenous immunoglobulin derived from healthy donors in Japan. Transfusion. 2021 Feb;61(2):356-360. https://doi.org/10.1111/trf.16161
Component-Based Phenotypes of Sepsis-Associated Disseminated Intravascular Coagulation and Clinical Outcomes Under the JAAM-2 Criteria The 34rd Congress of the International Society on Thrombosis and Haemostasis（ISTH） (2026)
Character and Formulation of Fibrinogen Cross-Linked by FXIII and/or FXIIIa Society for Biomaterials 2026 Annual Meeting &Exposition (2026)
Drug Repositioning Using Insoluble Fibrinogen Society for Biomaterials 2026 Annual Meeting &Exposition (2026)
Character and Formulation of Fibrinogen Cross-Linked by FXIII and/or FXIIIa European Society for Biomaterials 2025 (2025)
Drug Repositioning Using Insoluble Fibrinogen European Society for Biomaterials 2025 (2025)
Evaluating DIC resolution as a surrogate outcome for mortality in sepsis-associated DIC The 33rd Congress of the International Society on Thrombosis and Haemostasis（ISTH） (2025)
Risk stratification utilizing Sequential Organ Failure Assessment (SOFA) score, antithrombin activity, and demographic data in sepsis-associated disseminated intravascular coagulation (DIC) The 32nd Congress of the International Society on Thrombosis and Haemostasis（ISTH） (2024)
